Pterostilben

Innehåller 30 kapslar vilket motsvarar en månadsförbrukning.

Dosering: 1 kapsel dagligen i samband med måltid.

Ingredienser: Trans-pterostilben (Pterocarpus santalinus), fyllnadsmedel (Mikrokristallin cellulosa), klumpförebyggande medel (Kiseldioxid), vegetabilisk kapsel (Hydroxipropylmetylcellulosa).

Övrig information: Kosttillskott bör inte användas som ett alternativ till en varierad kost och en hälsosam, aktiv livsstil. Den rekommenderade dosen ska inte överskridas och bör för bästa resultat kombineras med varierad och näringsrik kost. Kapslarna ska förvaras i den förslutna burken utom räckhåll för barn. Förpackningen sorteras som plast.

1. Chan EWC, Wong CW, Tan YH, Foo JPY, Wong SK, Chan HT. Resveratrol and pterostilbene: A comparative overview of their chemistry, biosynthesis, plant sources and pharmacological properties. JAPS. 2019;9(7). DOI: 10.7324/JAPS.2019.90717
2. Daniel M Riche, David Deschamp, Michael E Griswold, Corey L McEwen, Krista D Riche, Justin J Sherman and Marion R Wofford. Abstract 617: Impact Of Pterostilbene On Blood Pressure and Other Metabolic Parameters In Adults. Hypertension. 2018;60(1).
3. Ding RR, Huang GY, Zhang YJ, et al. Pterostilbene Ameliorates Renal Damage in Diabetic Rats by Suppressing Hyperglycemia with Inhibition of Inflammatory and Fibrotic Responses. Biomed Environ Sci. 2021;34(12):1015-1019. doi:10.3967/bes2021.137
4. Gareri P, Castagna A, Cotroneo AM, Putignano S, De Sarro G, Bruni AC. The role of citicoline in cognitive impairment: pharmacological characteristics, possible advantages, and doubts for an old drug with new perspectives [published correction appears in Clin Interv Aging. 2015;10:1625]. Clin Interv Aging. 2015;10:1421-1429. Published 2015 Sep 3. doi:10.2147/CIA.S87886
5. Hougee S, Faber J, Sanders A, et al. Selective COX-2 inhibition by a Pterocarpus marsupium extract characterized by pterostilbene, and its activity in healthy human volunteers. Planta Med. 2005;71(5):387-392. doi:10.1055/s-2005-864130
6. Hu W, Yu H, Zhou X, et al. Topical administration of pterostilbene accelerates burn wound healing in diabetes through activation of the HIF1α signaling pathway [published online ahead of print, 2021 Nov 6]. Burns. 2021;S0305-4179(21)00306-5. doi:10.1016/j.burns.2021.10.019
7. Jaacks LM, Vandevijvere S, Pan A, et al. The obesity transition: stages of the global epidemic. Lancet Diabetes Endocrinol. 2019;7(3):231-240. doi:10.1016/S2213-8587(19)30026-9
8. Koh YC, Ho CT, Pan MH. Recent Advances in Health Benefits of Stilbenoids. J Agric Food Chem. 2021;69(35):10036-10057. DOI: 10.1021/acs.jafc.1c03699. Epub 2021 Aug 30. PMID: 34460268.
9. Kosuru R, Cai Y, Kandula V, et al. AMPK Contributes to Cardioprotective Effects of Pterostilbene Against Myocardial Ischemia-Reperfusion Injury in Diabetic Rats by Suppressing Cardiac Oxidative Stress and Apoptosis. Cell Physiol Biochem. 2018;46(4):1381-1397. doi:10.1159/000489154
10. Kosuru R, Rai U, Prakash S, Singh A, Singh S. Promising therapeutic potential of pterostilbene and its mechanistic insight based on preclinical evidence. Eur J Pharmacol. 2016;789:229-243. doi:10.1016/j.ejphar.2016.07.046
11. Lacerda D, Türck P, Campos-Carraro C, et al. pterostilbene improves cardiac function in a rat model of right heart failure through modulation of calcium handling proteins and oxidative stress. Appl Physiol Nutr Metab. 2020;45(9):987-995. doi:10.1139/apnm-2019-0864
12. Lange KW, Li S. Resveratrol, pterostilbene, and dementia. Biofactors. 2018;44(1):83-90. doi:10.1002/biof.1396
13. Liu Y, You Y, Lu J, Chen X, Yang Z. Recent Advances in Synthesis, Bioactivity, and Pharmacokinetics of Pterostilbene, an Important Analog of Resveratrol. Molecules. 2020;25(21):5166. Published 2020 Nov 6. doi:10.3390/molecules25215166
14. McCormack D, McFadden D. A review of pterostilbene antioxidant activity and disease modification. Oxid Med Cell Longev. 2013;2013:575482. doi:10.1155/2013/575482
15. Milton-Laskíbar I, Gómez-Zorita S, Arias N, et al. Effects of resveratrol and its derivative pterostilbene on brown adipose tissue thermogenic activation and on white adipose tissue browning process. J Physiol Biochem. 2020;76(2):269-278. doi:10.1007/s13105-020-00735-3
16. Özdaş S, Taştekin B, Gürgen SG, et al. Pterostilbene protects cochlea from ototoxicity in streptozotocin-induced diabetic rats by inhibiting apoptosis. PLoS One. 2020;15(7):e0228429. Published 2020 Jul 28. doi:10.1371/journal.pone.0228429
17. Pan MH, Wu JC, Ho CT, Lai CS. Antiobesity molecular mechanisms of action: Resveratrol and pterostilbene. Biofactors. 2018;44(1):50-60. doi:10.1002/biof.1409
18. Remsberg CM, Yáñez JA, Ohgami Y, Vega-Villa KR, Rimando AM, Davies NM. Pharmacometrics of pterostilbene: preclinical pharmacokinetics and metabolism, anticancer, anti-inflammatory, antioxidant and analgesic activity. Phytother Res. 2008;22(2):169-179. doi:10.1002/ptr.2277
19. Rui Z, Zhang L, Li X, et al. Pterostilbene exert an anti-arthritic effect by attenuating inflammation, oxidative stress, and alteration of gut microbiota [published online ahead of print, 2022 Jan 20]. J Food Biochem. 2022;e14011. doi:10.1111/jfbc.14011
20. Salleh NH, Zulkipli IN, Mohd Yasin H, et al. Systematic Review of Medicinal Plants Used for Treatment of Diabetes in Human Clinical Trials: An ASEAN Perspective. Evid Based Complement Alternat Med. 2021;2021:5570939. Published 2021 Oct 13. doi:10.1155/2021/5570939